Computer-driven funds, including Renaissance Technologies, considered one of the best in the world, are believed to have lost heavily almost across the board this week.

Bankers said quantitative funds run by Tykhe Capital, another US hedge fund manager, are down 20% for August so far, while JP Morgan's Highbridge Capital Management has lost 6% in its statistical arbitrage fund. Bankers said DE Shaw is down 5% while State Street Global Advisors has also lost money in its quantitative equity strategies this week. Renaissance is down 3% so far this month.